abstract：:Regenerative cell therapy is a promising therapeutic strategy in neurology, most notably to improve stroke recovery. Although tolerability and feasibility have apparently been validated, many questions remain as to what is the best type of cells to use, the best route and the post-stroke delay for administration. Two ...

journal_title：Revue neurologique

authors： Detante O,Rome C,Papassin J

更新日期：2017-11-01 00:00:00

abstract：AIM:In patients with cerebral ischemia, intravenous (i.v.) recombinant tissue plasminogen activator (rt-PA) increases survival without handicap or dependency despite an increased risk of bleeding. This study evaluated whether the results of randomized controlled trials are reproduced in clinical practice. METHOD:Data ...

journal_title：Revue neurologique

authors： Decourcelle A,Moulin S,Dequatre-Ponchelle N,Bodenant M,Rossi C,Girot M,Hénon H,Wiel E,Bordet R,Goldstein P,Pruvo JP,Cordonnier C,Leys D

更新日期：2017-06-01 00:00:00

abstract：:Within lower motor neuron diseases, benign focal amyotrophy is a rare syndrome characterized by insidious neurogenic asymmetric atrophy restricted to upper or lower limbs with a good prognosis over time. Described under several terms, the nosology is probably heterogeneous. In juvenile distal upper-limbs forms, specif...

journal_title：Revue neurologique

authors： Cintas P

更新日期：2017-05-01 00:00:00

abstract：:In classic amyotrophic lateral sclerosis (ALS), the relative degree of impairment of cortical vs spinal motor neurons serving the different body regions is highly variable. This means that an accurate, systematic assessment of the patient's clinical presentation is essential for both the diagnosis and prognosis. The p...

journal_title：Revue neurologique

authors： Tard C,Defebvre L,Moreau C,Devos D,Danel-Brunaud V

更新日期：2017-05-01 00:00:00

abstract：:Neuronal and/or axonal hyperactivity and hyperexcitability is an important feature of motor neuron diseases. It results clinically in cramps and fasciculations. It is not specific to motor neuron diseases, and can occur in healthy subjects, as well as in various pathologies of the peripheral nervous system, including ...

journal_title：Revue neurologique

authors： Grapperon AM,Attarian S

更新日期：2017-05-01 00:00:00

abstract：:Cerebral small vessel disease (SVD) is frequent in the elderly, and accounts for a wide spectrum of clinical and radiological manifestations. This report summarizes the most important findings obtained using diffusion MRI (DWI) in SVD. With DWI and apparent diffusion coefficient (ADC) maps, recent ischemic lesions can...

journal_title：Revue neurologique

authors： Lyoubi-Idrissi AL,Jouvent E,Poupon C,Chabriat H

更新日期：2017-04-01 00:00:00

abstract：:Neuropsychiatry had a profound impact on the life and work of one of the most influential French writers of the 20th century, Frédéric Sauser, better known by his pen name Blaise Cendrars (1887-1961). Cendrars, whose right writing hand was amputated after a battlefield wound in 1915, described with acuity his stump pa...

journal_title：Revue neurologique

authors： Tatu L,Bogousslavsky J

更新日期：2017-03-01 00:00:00

abstract：:Attention-Deficit/Hyperactivity Disorder (ADHD), although considered a childhood-onset neurodevelopmental condition, is nevertheless a frequent and disabling condition in adults. A proportion of such patients are not diagnosed during childhood or adolescence, as diagnosis of the syndrome is rather complex, especially ...

journal_title：Revue neurologique

authors： Magnin E,Maurs C

更新日期：2017-01-01 00:00:00

abstract：:Intracerebral hemorrhage (ICH) accounts for 15% of all strokes and approximately 50% of stroke-related mortality and disability worldwide. Patients who have experienced ICH are at high risk of negative outcome, including stroke and cognitive disorders. Vascular cognitive impairment are frequently seen after brain hemo...

journal_title：Revue neurologique

authors： Planton M,Raposo N,Danet L,Albucher JF,Péran P,Pariente J

更新日期：2017-01-01 00:00:00

abstract：:Hereditary neuropathies are the most common inherited neuromuscular diseases. Charcot-Marie-Tooth (CMT) disease represents the most common form with an average prevalence ranging from 1/2500 to 1/1200, depending on the studies. To date and with the advances of the latest generation sequencing, more than 80 genes have ...

journal_title：Revue neurologique

authors： Stojkovic T

更新日期：2016-12-01 00:00:00

abstract：:The emergence of life-logging technologies has led neuropsychologist to focus on understanding how this new technology could help patients with memory disorders. Despite the growing number of studies using life-logging technologies, a theoretical framework supporting its effectiveness is lacking. This review focuses o...

journal_title：Revue neurologique

authors： Dubourg L,Silva AR,Fitamen C,Moulin CJ,Souchay C

更新日期：2016-12-01 00:00:00

abstract：:The broad clinical spectrum of myotonic dystrophy type 1 (DM1) creates particular challenges for both medical care and design of clinical trials. Clinical onset spans a continuum from birth to late adulthood, with symptoms that are highly variable in both severity and nature of the affected organ systems. In the liter...

journal_title：Revue neurologique

authors： De Antonio M,Dogan C,Hamroun D,Mati M,Zerrouki S,Eymard B,Katsahian S,Bassez G,French Myotonic Dystrophy Clinical Network.

更新日期：2016-10-01 00:00:00

abstract：:The field of glycogenosis has been greatly expanded over the past few years with the discovery of new metabolic diseases that have allowed new metabolic pathways to be deciphered. Described here are the clinical and pathological features of four recently described muscle glycogenoses caused by GYS1, GYG1, RBCK1 and PG...

journal_title：Revue neurologique

authors： Laforêt P

更新日期：2016-10-01 00:00:00

abstract：:We are approaching the centenary of the first description of Guillain-Barré syndrome. The past 30 years had witnessed an amazing progress in the understanding of the immunological and pathological mechanisms of this disorder. We now recognize that Guillain-Barré syndrome is remarkably heterogeneous and under this umbr...

journal_title：Revue neurologique

authors： Uncini A

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Cognitive screening is crucial in Parkinson's disease (PD). However, there is still a lack of short tools in French. In this study, we aimed to compare the Parkinson Neuropsychometric Dementia Assessment (PANDA) with the Mini Mental Parkinson (MMP), the Mini Mental State Examination (MMSE) and the Clock Test...

journal_title：Revue neurologique

authors： Gasser AI,Calabrese P,Kalbe E,Kessler J,Rossier P

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:Evidence-based medicine is a difficult goal to achieve in rare diseases where randomized controlled trials are lacking. This report provides guidelines that capitalize on both the literature and expertise of the French National Huntington Disease Reference Centre to optimalize pharmacological therapeutic inte...

journal_title：Revue neurologique

authors： Désaméricq G,Youssov K,Charles P,Saleh N,Olivier A,Sherer-Gagou C,Verny C,multidisciplinary working group.,Bachoud-Lévi AC

更新日期：2016-01-01 00:00:00

abstract：:France is a country for which the epidemiology of migraine is very well known. Based on the results of the main studies over the last 20 years, this brief review presents the key descriptive data for French migraine epidemiology, and considers its prevalence, individual impact, recognition and medical management, and ...

journal_title：Revue neurologique

authors： Lanteri-Minet M,Géraud G

更新日期：2016-01-01 00:00:00

abstract：:Cognitive assessment among foreign patients is a growing need for several reasons: foreign patients have a different culture, they have an insufficient command of the language of the consulting center, and the available cognitive tools are largely unsuitable. For these reasons, we developed a non-verbal test of long-t...

journal_title：Revue neurologique

authors： Vanderaspoilden V,Nury D,Frisque J,Peigneux P

更新日期：2015-12-01 00:00:00

abstract：:The aim of this study was to evaluate the impact, on a regional scale (Franche-Comté), of 3 National Alzheimer care plans, particularly concerning the development of the offer of care management by clinicians as well as the panel of diagnoses concerned. Data on sociodemographic, neuropsychological and diagnostic chara...

journal_title：Revue neurologique

authors： Bereau M,Sylvestre G,Mauny F,Puyraveau M,Baudier F,Magnin E,Berger E,Vandel P,Galmiche J,Chopard G

更新日期：2015-09-01 00:00:00

abstract：:Massively parallel sequencing, otherwise known as high-throughput or next-generation sequencing, is rapidly gaining wide use in clinical practice due to possibility of simultaneous exploration of multiple genomic regions. More than 300 genes have been implicated in neuromuscular disorders, meaning that many genes need...

journal_title：Revue neurologique

authors： Gorokhova S,Biancalana V,Lévy N,Laporte J,Bartoli M,Krahn M

更新日期：2015-06-01 00:00:00

abstract：:Essential tremor is the most common movement disorder in adults. It is characterized by a postural and kinetic tremor affecting the arms, but it can also affect other body parts. It evolves gradually and can be responsible for a functional impairment in activities of daily living. Its pathophysiology remains poorly un...

journal_title：Revue neurologique

authors： Boutin E,Vaugoyeau M,Eusebio A,Azulay JP,Witjas T

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Stroke, as the third cause of death in developed countries, is a public health issue. Atrial fibrillation is an important cause of ischemic stroke and its prevention is efficient with oral anticoagulation. However, oral anticoagulation can be contraindicated because of hemorrhagic risk related to these treat...

journal_title：Revue neurologique

authors： Grosset-Janin D,Barth E,Bertrand B,Detante O

更新日期：2015-05-01 00:00:00

abstract：:The fact that epilepsy consists in multiple heterogeneous syndromes with different etiologies and different symptoms is insufficiently taken into account in current animal models. This is in particular the case when modeling mesiotemporal lobe epilepsy (MTLE) for which clinical, electrophysiological, histological and ...

journal_title：Revue neurologique

authors： Depaulis A,Hamelin S

更新日期：2015-03-01 00:00:00

abstract：:Before a patient can take part in a clinical research, French legislation requires his/her free, express and informed consent. In the same way, the information must be given in a clear, fair and appropriate manner. However, in the context of Alzheimer's disease, one might wonder about the patient's capacity to consent...

journal_title：Revue neurologique

authors： Bouyer C,Teulon M,Toullat G,Gil R

更新日期：2015-02-01 00:00:00

abstract：:In March 2012, the French Health Products Safety Agency interrupted the commercialization of di-hydan (phenytoin). It was replaced by diphantoïne (phenytoin sodium) and prescribers were informed that posology was equivalent for both products. We conducted a retrospective study of phenytoinemia and clinical effects com...

journal_title：Revue neurologique

authors： Lavandier N,Tourniaire D

更新日期：2015-02-01 00:00:00

abstract：:In this focus, we review, in the light of the recent literature, the modalities and indications of surgical cerebral revascularization for Moyamoya (MM) disease or syndrome. We also report our experience in the surgical management of adult MM. In symptomatic forms, with presence of severe disturbances of perfusion or ...

journal_title：Revue neurologique

authors： Thines L,Petyt G,Aguettaz P,Bodenant M,Himpens FX,Lenci H,Henon H,Gauthier C,Hossein-Foucher C,Cordonnier C,Lejeune JP

更新日期：2015-01-01 00:00:00

abstract：:The last decade has nourished strong doubts on the beneficial prospects of gene therapy for curing fatal diseases. However, this climate of reservation is currently being transcended by the publication of several successful clinical protocols, restoring confidence in the appropriateness of therapeutic gene transfer. A...

journal_title：Revue neurologique

authors： Serguera C,Bemelmans AP

更新日期：2014-12-01 00:00:00

abstract：INTRODUCTION:Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system. Prevalence of depression in MS is significant. Existence of mood disorders alters the patients' life quality. OBJECTIVE:To determine the prevalence of depression in MS and establish the relationship between the...

journal_title：Revue neurologique

authors： Mrabet S,Ben Ali N,Kchaou M,Belal S

更新日期：2014-11-01 00:00:00

abstract：:In most dysimmune neuropathies, historically the microscopical lesions were described prior to immunological studies. The latter along with neuropathological studies have found some immune, albeit incomplete, explanations of the mechanisms of these lesions which we will describe in two main syndromes: the primitive au...

journal_title：Revue neurologique

authors： Vallat JM

更新日期：2014-10-01 00:00:00

abstract：INTRODUCTION:Spasticity is a motor disorder, which can be treated by botulinum toxin (BT). We found no studies describing BT management of spasticity in Tunisian children. The aim of our study was to determine the frequency of spastic children treated with BT in the Tunisian hospital population and to evaluate treatmen...

journal_title：Revue neurologique

authors： Benrhouma H,Yacoubi J,Kraoua I,Klaa H,Ben Youssef-Turki I,Gouider-Khouja N

更新日期：2014-08-01 00:00:00

abstract：:Amusia is defined as an auditory agnosia, specifically related to music, resulting from a cerebral lesion or being of congenital origin. Amusia is rarely associated to musical anhedonia. We report the case of a 43-year-old patient who suffered in January 2012 from a right ischemic lesion affecting the superior tempora...

journal_title：Revue neurologique

authors： Hirel C,Lévêque Y,Deiana G,Richard N,Cho TH,Mechtouff L,Derex L,Tillmann B,Caclin A,Nighoghossian N

更新日期：2014-08-01 00:00:00

abstract：:Intravenous recombinant tissue plasminogen activator for acute ischemic stroke is contraindicated in patients harboring an asymptomatic intracranial vascular malformation, whether it is incidentally discovered at the time of the initial cerebral imaging or previously known. Because thrombolysis is associated with a ri...

journal_title：Revue neurologique

authors： Guillon B,Toulgoat F

更新日期：2014-06-01 00:00:00

abstract：:Biofeedback is a complementary non-pharmacological and non-surgical therapeutic developed over the last thirty years in the management of drug-resistant epilepsy. Biofeedback allows learning cognitive and behavioral strategies via a psychophysiological feedback loop. Firstly, this paper describes the different types o...

journal_title：Revue neurologique

authors： Micoulaud-Franchi JA,Lanteaume L,Pallanca O,Vion-Dury J,Bartolomei F

更新日期：2014-03-01 00:00:00

abstract：:Several instruments are used for the assessment of the disability, and the scale AGGIR (Autonomie Gérontologie Groupes Iso-Ressources) is the one most commonly used in France. This scale covers so-called instrumental dimensions, that correspond to relatively complex activities with the dominating cognitive component (...

journal_title：Revue neurologique

authors： Aguilova L,Sauzéon H,Balland É,Consel C,N'Kaoua B

更新日期：2014-03-01 00:00:00

abstract：INTRODUCTION:Movement disorders are uncommon in multiple sclerosis, except for tremor. Patients rarely have paroxysmal dystonia (or tonic spasm), which can be the presenting manifestation of the disease. OBSERVATIONS:Two videotaped observations are presented. The first patient was a 27-year-old woman, treated for rela...

journal_title：Revue neurologique

authors： El Otmani H,Benmansour Y,Araqi-Houssaini A,Benkirane N,Dany F,Abdoh Rafai M,El Moutawakil B,Slassi I

更新日期：2014-02-01 00:00:00

abstract：:Improvement of therapeutic strategies for peripheral neuropathies requires multicentric clinical trials. For chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), a randomized controlled multicentric study compared IgIV to pulses of methylprednisolone (MP) given for 6 months. The primary endpoint was treat...

journal_title：Revue neurologique

authors： Adams D

更新日期：2013-12-01 00:00:00

abstract：:The place of magnetic resonance imaging (MRI) in the monitoring of patients with multiple sclerosis (MS) is not codified except during the diagnostic phase. Several studies in the literature have shown that lesion load measured on an MRI done at the beginning of the disease or its increase during the first years had a...

journal_title：Revue neurologique

authors： Brochet B

更新日期：2013-11-01 00:00:00

abstract：:The last decade marked a turning point in the knowledge of frontotemporal lobar degenerations (FTLD). Major discoveries were made with the identification of TDP-43 and FUS, two novel key players in FTLD. The growing number of FTLD genes has considerably changed our clinical practice. The high intrafamilial variability...

journal_title：Revue neurologique

authors： Le Ber I

更新日期：2013-10-01 00:00:00

abstract：INTRODUCTION:In recent years, the advances of knowledge in clinical, genetic and epigenetic features of facioscapulohumeral muscular dystrophy (FSHD) allowed the identification of two forms of FSHD, the classical autosomal dominant FSHD type 1, and FSHD type 2 characterized by an identical clinical phenotype but associ...

journal_title：Revue neurologique

authors： Sacconi S,Desnuelle C

更新日期：2013-08-01 00:00:00

abstract：:The distal myopathies are a heterogeneous group of genetic disorders defined by a predominant distal weakness at onset or throughout the evolution of the disease and by pathological data supporting a myopathic process. The number of genes associated with distal myopathies continues to increase. Fourteen distinct dista...

journal_title：Revue neurologique

authors： Pénisson-Besnier I

更新日期：2013-08-01 00:00:00